Top Secret Nutrition's BCAA Hyperblend™ combines the power of branched-chain amino acids with ingredients designed to promote anabolic activity and enhance absorption to create the future of BCAA supplementation.

• Enhanced muscle protein synthesis
• Reduced muscle soreness
• Improved muscle recovery
• Reduced brain fatigue
• Increased energy levels
• Increased fat oxidation

Of the 20 amino acids that help build protein, nine of these cannot be synthesized in the human body. These nine compounds are referred to as essential amino acids because they must be consumed through food or supplements. Three of these essential amino acids - leucine, isoleucine, and valine - are branched-chain amino acids, or BCAAs. Unlike the other amino acids, BCAAs are metabolized in muscle rather than in the liver, which means that they play a critical role in muscle development because they reach muscle tissue faster. The more BCAAs you have in your muscles, the slower your muscle cells break down muscle fiber. The anabolic stimulus from your training remains the same, but you experience less muscle breakdown, so you can build up more muscle mass.

THE LEUCINE DEBATE
The research on leucine and how it relates to muscle protein synthesis (MPS) in humans is debated. Some studies report increased MPS while others show suppressed muscle protein breakdown without increased protein synthesis during leucine infusion. One point on which the studies agree is that leucine is anti-catabolic.* The debate is centered on just how anabolic leucine is in humans. Further studies on this topic conducted by the researchers from the University of Texas Medical Branch (Galveston) have discovered that leucine appears to promote anabolic signaling, but not protein anabolism. In other words, leucine stimulates the signal to activate muscle protein synthesis but does not actually make it happen. Additionally, they found that an infusion of 1.8 grams is sufficient stimulate the anabolic signal. Although leucine is definitely the MVP of the BCAA team, it should be combined with the other BCAAs valine and isoleucine for maximum effect.

VALINE AND BRAIN FATIGUE
Several research studies have confirmed that taking BCAAs, and in particular valine, before a workout lowers the amount of tryptophan that gets into the brain, thus lessening 5-HT levels and fatigue. Therefore, BCAA ingestion can help to prevent feeling fatigued during workouts, which will allow you to train harder and longer, encouraging greater muscle growth. BCAA supplementation can also help to enhance mood and brain function by reducing brain fatigue through this same mechanism.

ISOLEUCINE METABOLISM AND FAT LOSS
A recent animal study conducted in Japan Suggests that isoleucine is the BCAA that activates the proteins UCP2 and UCP3, which help boost metabolism. Animals in the isoleucine group had lower weight gain and almost 50% less white adipose tissue than the control group.

BCAA BLEND - A 3:1:1 ratio of leucine (clinically studied 1.8 grams) to isoleucine and valine.
ANABOLIC POWER BLEND - Ursolic acid and homobrassinolide have been included to enhance the anabolic and muscle protein synthesis stimulating effect of BCAAs.
ABSORPTION AND EFFECTIVENESS BLEND - Astravar™ and Bioperine help enhance the absorption of the other powerful ingredients.
VITAMIN B6 - Acts as a coenzyme to many other enzymes that are involved with metabolism in the body. Vitamin B6 plays a key role in amino acid metabolism and is involved in the first step in the metabolism of BCAAs via its role in catalyzing the enzyme aminotransferase

Directions:
For best results take 4 capsules anytime you want to enhance protein synthesis.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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