Been using the 410 about 3-4x a week since xmas, usually about 3mi. This thing is amazing, it really is. If you have trouble with the touch bezel you can always lock it using the two actual buttons.
I set what i want to see when i run and have it auto scroll. You get up to three pieces of information on up to four screens (if you use the HR monitor screen too). Mostly I just want to know my total time, pace and distance run. The virtual training partner is really helpful if you're like me and tend to overextend on your pacing. It gives you a little guy to run against and tells you how far ahead or behind you are. I'm shooting for a 9:50/mi pace, so that's what I set it at. For a while i had it show me heart rate but i turned that screen off although I still record it on the garmin connect website.
As for the extra parts, most notably the Garmin Connect website; it tracks pretty much everything. Time, distance, pace (average and instantaneous), HR, elevation and a whole mess of other things I haven't had time to delve in to. You can also use it to program exceedingly complex workouts and have them sent to the watch. You can do fairly simple ones on the watch itself too, but it's a bit of a PITA. Everything is transmitted via the ANT+ stick that plugs in to your USB port. Once you're within 30' it just does it automatically, no cables, no muss, no fuss.
The 610 is no doubt a better watch, but it also runs about $400. This selling for $130 is considerably cheaper than the lower models are selling for and is totally worth it if you ask me.